Faculty
Dr. Sean P. Keenan
Dr. Sean Keenan is a Clinical Associate Professor of Medicine at the University of British Columbia. He works as an Intensivist at the Royal Columbian Hospital in New Westminster, BC. He is also the Provincial Medical Director, Donation Services at BC Transplant.
| University or Institution | Degree | Subject Area | Dates |
| McMaster University | MSc(Epid) | Epidemiology | 1999/06 |
| University of Western Ontario | FRCPC | Critical Care | 1995/06 |
| University of British Columbia | FRCPC | Respiratory Medicine | 1991/06 |
| Dalhousie University | FRCPC | Internal Medicine | 1990/06 |
| University of Toronto | MD | 1980/07 – 1984/06 | |
| University of Toronto | Chem/Biochem – undergrad | 1978/07 – 1980/06 |
Title of Dissertation and Name of Supervisor
| Title of Dissertation | Supervisor |
| The relative effectiveness of noninvasive positive pressure ventilation and continuous positive airway pressure in preventing endotracheal intubation in patients with cardiogenic pulmonary edema. Masters of Science (1999) (Health Research Methodology). | Dr. Deborah Cook, McMaster University |
Continuing Education or Training
| University or Institution | Rank or Title | Dates |
| Fraser Health Authority | Completion of PQI Level 3 equivalent* | 2016/03 |
* 1-year course consisting of 12 full-day sessions and project work in between. Coursed based on IHI QI approach and expected commitment of FTE 0.2. I was a member of the first cohort of PQI in FHA and have continued QI work and teaching as a Faculty Member of FHA PQI
Continuing Medical Education
| University or Institution | Type | Detail | Dates | |
| 1 | University of British Columbia | 1-2 day conference | BC Transplant Education Days | 2018-2020 |
| 2 | University of British Columbia | Conference | Canadian Critical Care Conference, Whistler, BC
ECMO Workshop (2015) |
2015
2017 |
| 3 | Royal College of Physicians and Surgeons of Canada | Maintenance of Certification | 446
631.5 833 931 |
2016-2021
2011-2015 2006-2010 2002-2005 |
| 4 | University of Toronto | Conference | Critical Care Canada Forum, Toronto, Ont | 2008
2011 2015 2016 2017 2018 2020 |
| 5 | American Thoracic Society | Conference | Annual ATS Conference | 2008
2009 2012 |
| 6 | Society Critical Care Medicine | Conference | Annual SCCM Conference | 2011
2014 |
| 7 | Canadian Critical Care Trials Group | Conference | Annual CCCTG Conference, Lake Louise | 2008
2009 |
| 8 | Canadian Medical Association | PMI Courses
(2-day) |
a) Management Dynamics
b) Dollars and Sense: Finance and Economics for the Healthcare Leader c) Prescribing Quality Improvement d) Disruptive behaviour: a rationale approach for physician leaders e) Leading Change and Innovation |
2012
2012
2013
2013
2013 |
| 9 | BCPSQC | Conference | Annual Quality Forum | 2016
2021 |
Professional Qualifications
| 1 | Member: College of Physicians and Surgeons of BC (12877), since 1998 – active |
| 2 | Fellow of the Royal College of Physicians of Canada (392322) Critical Care Medicine 1995 to present |
| 3 | Fellow of the Royal College of Physicians of Canada (392322) Respiratory Medicine 1991 to present |
| 4 | Fellow of the Royal College of Physicians of Canada (392322) Internal Medicine 1990 to present |
| 5 | Certified, American Board of Internal Medicine 1996 |
| 6 | Licentiate: Medical Council of Canada, 1985 |
| 01. Refereed Publications | |||
| (a) Journals | |||
| 1. | Keenan S, Kramer A, Healey A, Weiss MJ, Dhanani S, Beed S, Djogovic D, Sullivan K, Shemie SD. The variable impact of the overdose crisis on organ donation among five Canadian provinces: a retrospective study.Can J Anaesth. 2021 Feb 9. doi: 10.1007/s12630-021-01945-z. Online ahead of print.PMID: 33564994 | ||
| 2. | Healey A, Hartwick M, Downar J, Keenan S, Lalani J, Mohr J, Appleby A, Spring J, Delaney JW, Wilson LC, Shemie S; for Canadian Blood Services, the Canadian Critical Care Society, the Canadian Association of Critical Care Nurses, and the Canadian Society of Palliative Care Physicians. Improving quality of withdrawal of life-sustaining measures in organ donation: a framework and implementation toolkit. Can J Anaesth. 2020 Nov;67(11):1549-1556. doi: 10.1007/s12630-020-01774-6. Epub 2020 Sep 11.PMID: 32918249 | ||
| 3. | Zheng K, Sutherland S, Cardinal P, Meade M, Landriault A, Vanderspank-Wright B, Valiani S, Shemie S, Appleby A, Keenan S, Weiss M, Werestiuk K, Kramer AH, Kawchuk J, Beed S, Dhanani S, Pagliarello G, Chasse M, Lotherington K, Gatien M, Parsons K, Chandler J, Nickerson P, Kutsogiannis J, Sarti AJ. Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives. BMJ Open. 2020 Jun 15;10(6):e037527. doi: 10.1136/bmjopen-2020-037527.PMID: 32540892 | ||
| 4. | Ball IM, Hornby L, Rochwerg B, Weiss MJ, Gillrie C, Chassé M, D’Aragon F, Meade MO, Soliman K, Ali A, Arora S, Basmaji J, Boyd JG, Cantin B, Chaudhury P, Cypel M, Freed D, Frenette AJ, Hruska P, Karvellas CJ, Keenan S, Kramer A, Kutsogiannis DJ, Lien D, Luke P, Mahoney M, Singh JM, Wilson LC, Wright A, Zaltzman J, Shemie SD. Management of the neurologically deceased organ donor: A Canadian clinical practice guideline. CMAJ. 2020 Apr 6;192(14):E361-E369. doi: 10.1503/cmaj.190631.PMID: 32392524 | ||
| 5. | D’Aragon F, Lamontagne F, Cook D, Dhanani S, Keenan S, Chassé M, English S, Burns KEA, Frenette AJ, Ball I, Boyd JG, Masse MH, Breau R, Akhtar A, Kramer A, Rochwerg B, Lauzier F, Kutsogiannis DJ, Ibrahim Q, Hand L, Zhou Q, Meade MO; Canadian Critical Care Trials Group and the Canadian Donation and Transplant Research Program. Variability in deceased donor care in Canada: a report of the Canada-DONATE cohort study. Can J Anaesth. 2020 Aug;67(8):992-1004. doi: 10.1007/s12630-020-01692-7. Epub 2020 May 8.PMID: 32385825 English. | ||
| 6. | Kramer AH, Holliday K, Keenan S, Isac G, Kutsogiannis DJ, Kneteman NM, Robertson A, Nickerson P, Tibbles LA. Donation after circulatory determination of death in western Canada: a multicentre study of donor characteristics and critical care practices. Can J Anaesth. 2020 May;67(5):521-531. doi: 10.1007/s12630-020-01594-8. Epub 2020 Feb 25.PMID: 32100271 | ||
| 7. | Ball IM, Healey A, Keenan S, Priestap F, Basmaji J, Honarmand K, Parsons Leigh J, Shemie S, Chaudhury P, Singh JM, Zaltzman J, Beed S, Weiss M. Organ Donation after Medical Assistance in Dying – Canada’s First Cases. N Engl J Med. 2020 Feb 6;382(6):576-577. doi: 10.1056/NEJMc1915485.PMID: 32023380 | ||
| 8. | Kok B, Karvellas CJ, Abraldes JG, Jalan R, Sundaram V, Gurka D, Keenan S, Kumar A, Martinka G, Bookatz B, Wood G, Kumar A; Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Research Group. The impact of obesity in cirrhotic patients with septic shock: A retrospective cohort study. Liver Int. 2018 Jul;38(7):1230-1241. doi: 10.1111/liv.13648. Epub 2017 Dec 18. PMID:9194916 | ||
| 9. | Henrich NJ, Dodek PM, Gladstone E, Alden L, Keenan SP, Reynolds S, Rodney P.Consequences of Moral Distress in the Intensive Care Unit: A Qualitative Study. Am J Crit Care. 2017 Jul;26(4):e48-e57. doi: 10.4037/ajcc2017 | ||
| 10. | Rochwerg B, Brochard L, Elliott MW, Hess D, Hill NS, Nava S, Navalesi P Members Of The Steering Committee, Antonelli M, Brozek J, Conti G, Ferrer M, Guntupalli K, Jaber S, Keenan S, Mancebo J, Mehta S, Raoof S Members Of The Task Force. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J. 2017 Aug 31;50(2). pii: 1602426. doi: 10.1183/13993003.02426-2016. Print 2017 Aug | ||
| 11. | D’Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chassé M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO; Canadian Critical Care Trials Group and the Canadian National Transplant Research Program.Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors. BMJ Open. 2017 Sep 28;7(9):e018858. doi: 10.1136/bmjopen-2017-018858 | ||
| 12. | Amaral AC, Fowler RA, Pinto R, Rubenfeld GD, Ellis P, Bookatz B, Marshall JC, Martinka G, Keenan S, Laporta D, Roberts D, Kumar A; Cooperative Antimicrobial Therapy of Septic Shock Database Research Group. Patient and Organizational Factors Associated With Delays in Antimicrobial Therapy for Septic Shock. Crit Care Med. 2016 Dec;44(12):2145-2153. | ||
| 13. | Henrich NJ, Dodek PM, Alden L, Keenan SP, Reynolds S, Rodney P. Causes of moral distress in the intensive care unit: A qualitative study. J Crit Care. 2016 Oct;35:57-62. doi: 10.1016/j.jcrc.2016.04.033. Epub 2016 May | ||
| 14. | Burry L, Cook D, Herridge M, Devlin JW, Fergusson D, Meade M, Steinberg M, Skrobik Y, Olafson K, Burns K, Dodek P, Granton J, Ferguson N, Jacka M, Tanios M, Fowler R, Reynolds S, Keenan S, Mallick R, Mehta S; SLEAP Investigators; Canadian Critical Care Trials Group. Recall of ICU Stay in Patients Managed With a Sedation Protocol or a Sedation Protocol With Daily Interruption. Crit Care Med. 2015 Oct;43(10):2180-90. doi: 10.1097/CCM.0000000000001196. | ||
| 15. | Digby GC, Keenan SP, Parker CM, Sinuff T, Burns KE, Mehta S, Ronco JJ, Kutsogiannis DJ, Rose L, Ayas NT, Berthiaume LR, D’Arsigny CL, Stollery DE, Muscedere J.Noninvasive ventilation practice patterns for acute respiratory failure in Canadian tertiary care centres: A descriptive analysis. Can Respir J. 2015 Nov-Dec;22(6):331-40. Epub 2015 Oct 15 | ||
| 16. | Rose L, Burry L, Mallick R, Luk E, Cook D, Fergusson D, Dodek P, Burns K, Granton J, Ferguson N, Devlin JW, Steinberg M, Keenan S, Reynolds S, Tanios M, Fowler RA, Jacka M, Olafson K, Skrobik Y, Mehta S. Prevalence, risk factors, and outcomes associated with physical restraint use in mechanically ventilated adults.J Crit Care. 2016 Feb;31(1):31-5. doi: 10.1016/j.jcrc.2015.09.011. Epub 2015 Sep 25. | ||
| 17. | Dodek PM, Wong H, Norena M, Ayas N, Reynolds SR, Keenan SP, Hamric A, Rodney P, Stewart M, Alden L. Moral Distress in ICU Professionals is Associated with Profession, Age, and Years of Experience Journal of J Crit Care. 2016 Feb;31(1):178-82. doi: 10.1016/j.jcrc.2015.10.011. Epub 2015 Oct 20. | ||
| 18. | Boyce K, Dillon EC, Perrott J, Malyuk DL, Mabasa VH, Attfield E, McCormack G, Keenan S. Drug-Use Evaluation Comparing Dexmedetomidine Use at 3 Health Authority Sites Relative to Manufacturer’s Recommended Directions (DECODE Study). Can J Hosp Pharm 2014; 67(5):379-386 | ||
| 19. | Cook DJ, Ferguson ND, Hand L, Austin P, Zhou Q, Adhikari NK, Danesh V, Arabi Y, Matte AL, Clarke FE, Mehta S, Smith O, Wise MP, Friedrich JO, Keenan SP, Hanna S, Meade MO; OSCILLation for ARDS Treated Early Investigators; Canadian Critical Care Trials Group. Coenrollment in a randomized trial of High-frequency oscillation: prevalence, patterns, predictors and outcomes. Crit Care Med 2015;43:328-338 | ||
| 20. | Mehta S, Cook D, Devlin JW, Skrobik Y, Meade M, Fergusson D, Herridge M, Steinbery M, Granton J, Ferguson N, Tanios , Dodek P, Fowler R, Burns K, Jacka M, Olafson K, Mallick R, Reynolds S, Keenan S, Burry L; SLEAP Investigators: Canadian Critical Care Trials Group. Prevalence, risk factors, and outcomes of delirium in mechanically ventilated adults. Crit Care Med 2015;43:557-566 | ||
| 21. | Burry L, Cook D, Herridge M, Devlin JM, Fergusson D, Meade M, Steinberg M, Skrobnik Y, OlafsonK, Burns K, Dodek P, GrantonJ, Ferguson N, Jacka M, Tanios M, Fowler R, Reynolds S, Keenan S, Mallick R, Mehta S; SLEAP Investigators and the Canadian Critical Care Trials Group. Recall of ICU stay in patients managed with a sedation protocol or a sedation protocol with daily interruption. Crit Care Med 2015; 43:218-2190 | ||
| 22. | Sood M, Mandelzweig K, Rigatto C, Tangri N, Komenda P, Martinka G, Arabi Y, Keenan S, Kumar A; Cooperative Antimicrobial Therapy in Septic Shock (CATSS) Database Research Group. Non-pulmonary infections but not specific pathogens are associated withincreased risk of AKI in septic shock. Intensive Care Med 2014; 40:1080-1088 | ||
| 23. | Sood MM, Shafer LA, Ho J, Reslerova M, Martinka G, Keenan S, Dial S, Wood G, Rigatto C, Kumar A; Cooperative Antimicrobial Therapy in Septic Shock (CATSS) Database Research Group. Early reversible acute kidney injury is associated with improved survival in septic shock. J Crit Care 2014; 29:711-717 | ||
| 24. | Dodek PM, Norena M, Wong H, Keenan S, Martin C. Assessing the influence of intensive care unit organizational factors on outcomes in Canada: Is there residual confounding? J Intensive Care Med 2015; 30:413-419 | ||
| 25. | Muschedere J, Sinuff T, Heyland DK, Dodek PH, Keenan SP, Wood G, Jiang X, Day AG, Laporta D, Klompas M; Canadian Critical Care Trials Group. The clinical impact and preventability of ventilator-associated conditions in critically ill patients who are mechanically ventilated. Chest 2013; 144:1453-1460 | ||
| 26. | Cook D, Arabi Y, Ferguson N, Heels-Ansdell D, Freitag A, McDonald E, Clarke F, Keenan S, Pagliarello G, Plaxton W, Herridge M, Karachi T, Vallance S, Cade J, Crozier T, Alves da Silva S, Dosta Filho R, Brandao N, Watpool I, McArdle T, Hollinger G, Mandourah Y, Al-Hazmi M, Zytaruk N, Adhikari NK; PROTECT Researach Coordinators: PROTECT Investigators: Canadian Critical Care Trials Group: Australian and New Zealand Intensive Care Society Clinical Trials Group. Physicians declining patient enrollment in a critical trial: a case study in thromboprophylaxis. Intensive Care Med 2013; 39:2115-2125 | ||
| 27. | Arabi YM, Dara SI, Tamim HM, Rishu AH, Bouchama A, Khedr MK, Feinstein D, Parrillo JE, Wood KE, Keenan S, Zanotti S, Martinka G, Kumar A Clinical characteristic, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study. Crit Care 2013 Apri 17, 17(2) R72 | ||
| 28. | Burns KE, Meade MO, Lessard MR, Hand L, Zhou Q, Keenan SP, Lellouche F. Wean earlier and automatically with new technology (The WEAN Study): a multicenter, pilot randomized controlled trial. Am J Respir Crit Care Med 2013 Mar 22 PMID: 23525929 | ||
| 29. | Sinuff T, Muscedere J, Cook DJ, Dodek PM, Anderson W, Keenan SP, Wood G, Tan R, Haupt MT, Miletin M, Bouali R, Jiang X, Day AG, Overvelde J, Heyland DK, Canadian Critical Care Trials Group. Implementation of clinical practice guidelines for ventilator-associated pneumonia: a multicenter prospeictive study. Crit Care Med 2013;41:15-23 | ||
| 30. | Keenan SP, Sinuff T, Burns KE, Muscedere J, Kutsogiannis J, Mehta S, Cook Dj, Ayas N, Adhikari NK, Hand L, Scales DC, Pagnotta R, Lazosky L, Rocker G, Dial S, Laupland K, Sanders K, Dodek P for Candian Critical Care trials Group/ Candian Critical Care Society Noninvasive Ventilation Guidelines Group. Clinical practice guidelines for the use of noninvasive positive-pressur ventilation and noninvasive continuous positive airway pressure in the acute setting. CMAJ 2011;183:E195-214. | ||
| 31. | |||
| 32. | Dodek PM, Keenan SP, Norena M, Martin C, Wong H. Structure, process and outcome of all intensive care units within the province of British Columbia, Canada. J Intensiv Care 2010;25:149-55.Epub 2010Jan 21, | ||
| 33. | Dubord J, Dodek PM, Chan K, Keenan SP, Marion S, Wong H. In-hospital death in critically ill patients who have congestive heart failure: does size of hospital matter? Am J Med Qual 2010, 25;95-101 | ||
| 34. | Burns KE, Meade MO, Lessard MR, Keenan SP, Lellouche F. Wean Earlier and Automatically with New technology (the WEAN study): a protocol of a multicentre, pilot randomized controlled trial. Trials. 2009 Sep 4;10:81 | ||
| 35. | Burns KEA, Adhikari NKJ, Keenan SP, Meade M. Noninvasive ventilation to wean critically ill adults from invasive mechanical ventilation: a meta-analysis update. BMJ 2009;338:b1574 | ||
| 36. | Martin CM, Priestap F, Fisher H, Fowler RA, Heyland DK, Keenan SP, Longo C, Morrison T, Bentley D, Antman N. Outcomes, prevalence and incidence for patients with severe sepsis in a prospective, observational registry: The Canadian Sepsis Treatment and Response (STAR) Registry. Crit Care Med 2009 Jan;37(1):81-8. | ||
| 37. | Keenan SP, Mehta S. Noninvasive positive pressure ventilation for patients presenting with acute respiratory failure: the randomized controlled trials. Resp Care 2009, Jan;54(1):116-26. | ||
| 38. | Mehta S, Al-Hashim AK, Keenan SP. Noninvasive positive pressure ventilation in patients with acute cardiogenic pulmonary edema. Resp Care 2009,Feb;54(2):186-97. | ||
| 39. | Muscedere J, Dodek PM, Keenan SP, Fowler R, Cook D, Heyland D for the VAP Guideline Committee and the Canadian Critical Care Trials Group. Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Prevention J Crit Care 2008, 23; 126-137. | ||
| 40. | Muscedere J, Dodek PM, Keenan SP, Fowler R, Cook DJ, Heyland DK for the VAP Guideline Committee and the Canadian Critical Care Trials Group. Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Diagnosis and Treatment. J Crit Care 2008, 23; 138-147 | ||
| 41. | Belway D, Dodek PM, Keenan SP, Norena M, Wong H. The Role of Transport Intervals in Outcomes for Critically Ill Patients Who Are Transferred to Referral Centers. J Crit Care 2008; 23:287-294 | ||
| 42. | Sinuff T, Cook DJ, Keenan SP, Adhikari N, Eva K, Mehta S, Burns K, Rocker G, Hill NS. Noninvasive Ventilation for AcuteRespiratory Failure Near the End-of-Life. Crit Care Med 2008; 36:789-794 | ||
| 43. | Sweet DD, Naismith A, Keenan SP, Sinuff T, Dodek PM. Missed opportunities for noninvasive positive pressure ventilation: a utilization review. J Crit Care 2008; 23:111-117. | ||
| 44. | O’Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk D, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Kaplan A, Keenan S, Lacasse Y, Maltais F, Road J, Rocker G, Sin D, Sinuff T, Voduc N. Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease – 2007 update. Can Respir J 2007;14(Suppl):5B-32B. | ||
| 45. | Keenan SP, Martin CM, Norena M, Wong H, Priestap F, Dodek PM. Variation in length of ICU stay in patients admitted post-cardiac arrest. Crit Care Med 2007; 35:836-841. | ||
| 46. | Curtis JR, Cook DJ, Sinuff T, White DB, Hill N, Keenan S, Benditt JO, Kacmarek R, Kirchhoff KT, Levy MM. Noninvasive positive pressure ventilation in critical and palliative care settings: Understanding the goals of therapy. Critical Care Medicine 2007; 35:932-939. |
||
| 47. | Norena M, Wong H, Thompson WD, Keenan SP, Dodek PM. Severity of Illness and Comorbidity Scores as Predictors of Intensive Care Outcomes. J Crit Care 2006; 21:142-150 | ||
| 48. | Belway D, Henderson W, Keenan SP, Levy A, Dodek PM. The Effect of Pretransport Stabilization and Specialization of Transport Personnel on Outcome of Critically Ill Patients Transferred Between Hospitals: A Systematic Review of the Literature. J Crit Care 2006; 21:8-17 | ||
| 49. | Alvarez CM, Tredwell S, Keenan SP, Beauchamp R, De Vera M, Choit R. Treatment of Idiopathic Clubfoot utilizing Botulinum A Toxin: a new method and its short term outcome. J Pediatr Orthop 2005 Mar-Apr;25(2):229-35. | ||
| 50. | Keenan SP, Powers C, McCormack DG. Noninvasive ventilation in milder COPD exacerbations: an RCT. Respiratory Care 2005 May;50(5):610-6 | ||
| 51. | Keenan SP, Sinuff T, Cook DJ, Hill N. Does noninvasive positive pressure ventilation improve outcome in acute hypoxemic respiratory failure? A systematic review. Crit Care Med 2004; 32:2516-2523 | ||
| 52. | Dodek PM, Keenan SP, Cook DJ, et al. Evidence based clinical practice guideline for the prevention of ventilator-associated pneumonia. Ann Intern Med 2004; 141:305-313 | ||
| 53. | Sinuff T, Keenan SP. A clinical practice guideline for the use of noninvasive positive pressure ventilation in COPD patients with acute respiratory failure. J Crit Care 2004; 19:82-91 | ||
| 54. | Keenan SP, Chan K, Simon M, Levy AR, Hogg R, Spinelli J, Craib K, Dodek P. ICU Survivors have fewer hospital readmissions and readmission days than other hospitalized patients. Crit Care Med 2004: 32:391-398 | ||
| 55. | Keenan SP, Sinuff T, Cook DJ, Hill NS. When is the addition of noninvasive positive pressure ventilation effective in acute exacerbations of COPD? A systemic review of the literature. Ann Intern Med. 2003 Jun 3;138(11):861-70 | ||
| 56. | Keenan SP, Hogg R, Chan K, Craib K, Anis A, Spinelli J, Dodek P. Length of ICU and hospital stay for Chronic Obstructive Pulmonary Disease (COPD) varies among large community hospitals. Intensive Care Med, 2003 March 15 | ||
| 57. | Keenan SP, Mawdsley C, Plotkin D, Kossuth J, Sibbald WJ, for the Critical Care Research Network. Inter-hospital variability in withdrawal of life support: room for improvement? Crit Care Med 2003 Feb;31(2):626-31 | ||
| 58. | Keenan SP, Powers C, Block G, McCormack DG. Noninvasive ventilation (NPPV) for post-extubation respiratory failure: a randomized, controlled trial. JAMA 2002;287(24):3238-44 | ||
| 59. | Keenan SP. Use of real-time ultrasound to place central lines. J Crit Care 2002;17(2):126-37 | ||
| 60. | Keenan SP, Kossuth J, Eberhard J, Hoffmaster B, Sibbald WJ. Attitudes regarding organ donation from non-heart-beating donors. J Crit Care 2002; 17:29-36 | ||
| 61. | Keenan SP, Dodek PD, Chan K, Hogg RS, Craib KJP, Anis AJ, Spinelli JJ. Intensive care unit admission has minimal impact on long-term mortality. Crit Care Med, 2002; 30:501-507 | ||
| 62. | Brooks D, Anderson CM, Carter MA, Downes LA, Keenan SP, Kelsey CJ, Lacy JB. Clinical practice guidelines for suctioning the airway of the intubated and nonintubated patient. Can Respir J 2001; 8(3):163-181 | ||
| 63. | Keenan SP, Mawdsley C, Plotkin D, Priestap F, Webster G. Withdrawal of life support: how the family feels and why. J Palliative Care 2000 Oct; 16 Suppl:S40-S44 | ||
| 64. | Ostermann M, Keenan SP, Sieferling R, Sibbald WJ. A systematic review of the evidence supporting the use of sedative agents in the intensive care unit. JAMA 2000; 283:1451-1459 | ||
| 65. | Keenan SP, Martin CM, Kossuth J, Eberhard J, Sibbald W. Critical Care Research Network (CCRNet): a partnership in community-based research and research transfer. J Eval Clin Pract,2000; 6:15-22 | ||
| 66. | Keenan SP, Gregor JC, Cook DJ, Gafni A, Sibbald WJ. Is the addition of noninvasive positive pressure ventilation in severe acute exacerbations of chronic obstructive pulmonary disease cost-effective? Crit Care Med 2000; 28:2094-2102 | ||
| 67. | Keenan SP, Jaeschke R, Guyatt G, Cook DJ, Heyland D, Sibbald WJ, for the Evidenced Based Medicine in Critical Care Group. How to use articles about diagnostic technology: gastric tonometry. Crit Care Med 1999; 27:1726-1731. | ||
| 68. | Bulter R, Keenan SP, Inman KJ, Sibbald WJ, Block G. Is there a preferred technique for weaning the difficult to wean patient? A systematic review of the literature. Crit Care Med 1999; 27:2331-2336. | ||
| 69. | Heyland DK, Cook DJ, Griffith LE, Keenan SP, Brun-Buisson C. The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. Am J Respir Crit Care Med 1999; 159:1249-1256 | ||
| 70. | Heyland D, Kernerman P, Gafni A, Keenan SP, Chalfin D, for the Evidence Based Medicine in Critical Care Group . Users Guide for assessment of an economic analysis. Crit Care Med, 1999; 27:1195-1202 | ||
| 71. | Keenan SP, Montgomery J, Chen LM, Esmail R, Inman KJ, Sibbald WJ. The structure and process of ICU ventilatory care in a selection of Ontario hospitals. Intensiv Care Med, 1998; 24(9):946-952 | ||
| 72. | Pang D, Keenan SP, Cook DJ, Sibbald WJ. The effect of positive airway support on mortality and the need for intubation in cardiogenic pulmonary edema: a systematic review. Chest, 1998; 114(4):1185-1192 | ||
| 73. | Chen LM, Martin CM, Keenan SP, Sibbald WJ. Patients readmitted to the intensive care unit during the same hospitalization: clinical features and outcomes. Crit Care Med 1998; 26(11):1834-1841 | ||
| 74. | Kojlak J, Keenan SP, Plotkin D, Fish N, Esmail R. Are the bereavement needs of families and healthcare workers currently being met? CACCN 1998;9-1:12-16 | ||
| 75. | Keenan SP, Ferguson KA, Chan-Yeung M, Fleetham JA. Prevalence of sleep disordered breathing in a population of Canadian grainworkers. Can Respir J 1998; 5(3):184-190. | ||
| 76. | Keenan SP, Massel D, Inman KJ, Sibbald WJ. A systematic review of the cost-effectiveness of non-cardiac transitional care units. Chest 1998; 113:172-177 | ||
| 77. | Keenan SP, Busche KD, Chen LM, Esmail R, Sibbald WJ, Inman KJ. The withdrawal and withholding of life support in the intensive care unit: a comparison between teaching and community hospitals. Crit Care Med 1998;26:245-51. | ||
| 78. | Keenan SP, Kernerman P, Cook D, Martin CM, McCormack D, Sibbald WJ. The effects of noninvasive positive pressure ventilation on mortality in patients with acute respiratory failure: a meta-analysis. Crit Care Med 1997; 25:1685-92. | ||
| 79. | Jaeschke R, Meade M, Guyatt G, Keenan SP, Cook D, for the Evidenced Based Medicine in Critical Care Group. How to use diagnostic test articles in the ICU. Crit Care Med 1997; 25:1514-1521 | ||
| 80. | Keenan SP, Busche KD, Chen LM, McCarthy L, Inman KJ, Sibbald WJ. A retrospective review of a large cohort of patients undergoing the process of withholding or withdrawal of life support. Crit Care Med 1997; 25:1324-1331 | ||
| 81. | Keenan SP, Doig GS, Martin CM, Inman KJ, Sibbald WJ. Assessing the efficiency of the admission process to a critical care unit: does the literature allow the use of benchmarking? Intensive Care Med 1997; 23:574-580 | ||
| 82. | Ferguson KA, Ono T, Lowe AA, Keenan SP, Fleetham JA. A randomized, cross-over study of an oral appliance versus nasal continuous positive airway pressure in the treatment of mild-moderate obstructive sleep apnea. Chest 1996;109:1269-75. | ||
| 83. | Keenan SP, Alexander D, Buckle P, Road JD, Ryan CF, Oger J, Wilcox PG. Ventilatory muscle endurance as an indicator of muscle weakness in myasthenia gravis. Eur Respir J., 1995;8:1130-35 | ||
| 84. | Keenan SP, Burt H, Ryan CF, Fleetham JA. Long-term survival of patients with obstructive sleep apnea treated with either uvulopalatopharygoplasty or nasal CPAP. Chest 1994;105:155-159. | ||
| 85. | Keenan SP, Anderson B, Wiggs B, Ryan CF, Fleetham JA. The predictive accuracy of home oximetry in patients with suspected obstructive sleep apnea. Sleep 1993;16:S133-S134 | ||
| 86. | Bhatt MH, Keenan SP, Fleetham JA, Calne DB. Pleuropulmonary disease associated with dopamine agonists. Ann Neurol 1991; 30:613-16 | ||
| 02. Non-Refereed Publications | |||
| (b) Journals | |||
| 1. | Keenan SP. Nonivasive ventilation in acute lung injury: caution is good, more evidence is better. Respir Care 2010; 55:1757-1759. | ||
| 2. | Keenan SP, Winston B. Interfaces for noninvasive ventilation: Does it matter? J Bras Pneumol | ||
| 3. | Keenan SP. Noninvasive ventilation: trying to minimize harm? Crit Care Med 2008; 36:2937-2939 | ||
| 4. | Keenan SP. Noninvasive positive pressure ventilation for patients with acute hypoxemic respiratory failure? Expert Review of Resp Med February 2008;2:55-62 | ||
| 5. | Keenan SP. Moving beyond the numbers … the next step forward in improving patient care. Crit Care Med 2007; 35:960-961. | ||
| 6. | Keenan SP. Commentary on “Streptokinase did not reduce mortality or need for surgical drainage in pleural infection” ACP J Club 2005. Comment on: Makell NA, Davies CWH, Nunn AJ et al. UK controlled trial of intrapleural Streptokinase for pleural infection. N Engl J Med 2005; 352:865-874 | ||
| 7. | Keenan SP. Improving end-of-life care: Targeting what we can. Crit Care Med 2004;32:1230-1231 | ||
| 8. | Girault C, Auriant I, Keenan SP. Differences in Success Rates of Noninvasive Ventilation JAMA, Nov 2002; 288: 2540. |
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| 9. | Keenan SP. Weaning protocols: here to stay. Lancet 2002; 359:186-187 | ||
| 10. | Keenan SP, Heyland DK, Jacka MJ, Cook DJ, Dodek P. Ventilator associated pneumonia: prevention, diagnosis and treatment. Crit Care Clinics 2002; 18:107-125 | ||
| 11. | Lavis JN, Keenan SP. Bringing Health-Services Research to (and from) Critical Care. J Crit Care 2001; 16:127-132 | ||
| 12. | Keenan SP. How to care when cure is no longer possible. Lancet 2001; 358:676 | ||
| 13. | Keenan SP. Measuring level of sedation in the intensive care unit. JAMA 2000; 284(4):441-442 | ||
| 14. | Keenan SP. Sedation in the Critical Care Unit. Crit Care Rounds Nov/Dec 2000; 1(3) | ||
| 15. | Keenan SP. Commentary on “Invasive versus noninvasive diagnosis of ventilator associated pneumonia.” ACP J Club 2000, Nov-Dec; 133:93. Comment on: Fagon JY, Chastre J, Wolff M et al. Invasive and noninvasive strategies for management of suspected ventilator-associated pneumonia. A randomized trial. Ann Intern Med 2000; 132:621-630 | ||
| 16. | Keenan SP. Noninvasive positive pressure ventilation in acute respiratory failure. JAMA 2000; 284:2376-2378 | ||
| 17. | Keenan SP. Commentary on “Noninvasive positive-pressure ventilation was as effective as conventional mechanical ventilation and had fewer complications.” ACP J Club. 1999 Jan-Feb;130:10. Comment on: Antonelli M, Conti G, Rocco M, et al. A comparison of noninvasive ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 1998; 339:429-435 | ||
| 18. | Keenan SP, Martin CM. Creation of a Critical Care Research Network. Curr Op Crit Care, 1998; 4:470-475. | ||
| 19. | Keenan SP, Brake D. An Evidence Based Approach to noninvasive ventilation in acute respiratory failure. Crit Care Clin. 1998; 14(3):359-373 | ||
| 20. | Sibbald WJ, Keenan SP. Show me the evidence: a critical appraisal of the Pulmonary Artery Concensus Conference and other musings on how critical care practitioners need to improve the way we conduct business. Crit Care Med 1997; 25:2060-2063 | ||
| 21. | Keenan SP, Martin CM, Cook DJ, Sibbald. An evidence-based learning and teaching tool: the critically appraised topic (CAT). Crit Care 1997, Introductory Issue:19-22. | ||
| (c) Other |
| Abstracts |
| Keenan SP, Burt H, Ryan CF, Fleetham JA. Long-term survival of patients with obstructive sleep apnea treated with uvulopalatopharyngoplasty vs. nasal CPAP. Am Rev Respir Dis 1991; 143: A588 |
| Keenan SP, Burt H, Ryan CF, Fleetham JA. Chronic nasal CPAP therapy reduces systemic hypertension in patients with obstructive sleep apnea. Am Rev Respir Dis 1991; 143: A608. |
| Burt H, Keenan SP, Fleetham JA. Efficacy of different inhalation techniques with a breath-actuated dry powder beta-agonist inhaler. Am Rev Respir Dis 1991; 143: A655 |
| Bhatt MH, Keenan SP, Fleetham JA, Calne DB. Pleuropulmonary disease associated with Dopamine agonist therapy. Presented at the 10th International Symposium on Parkinson’s Disease, 1991. |
| Keenan SP, Anderson B, Wiggs B, Fleetham JA. The predictive accuracy of screening techniques in patients with obstructive sleep apnea. Am Rev Respir Dis 1992; 145: A723 |
| Keenan SP, Anderson B, Wiggs B, Fleetham JA. Home to hospital variability of screening tests for suspected obstructive sleep apnea. Am Rev Respir Dis 1992; 145: A723. |
| Anderson B, Keenan SP, Wiggs B, Fleetham JA. 2%, 3% or 4% arterial oxygen desaturations as a screening test for suspected obstructive sleep apnea? Am Rev Respir Dis 1992; 145: A723. |
| Keenan SP, Ryan CF, Fleetham JA. Sleep disordered breathing following acute spinal cord injury. Am Rev Respir Dis 1993; 147:A688. |
| Keenan SP, Anderson B, Wiggs B, Fleetham JA. The predictive accuracy of home oximetry in patients with suspected obstructive sleep apnea. Am Rev Respir Dis 1993; 147:A809. |
| Keenan SP, Marabini A, Ferguson K, Ward H, Chan-Yeng M, Fleetham JA. Prevalence of obstructive sleep apnea in a large population of grainworkers. Am Rev Respir Dis 1993; 147:A234. |
| Ferguson KA, Keenan SP, Anderson B, Fleetham JA. Validation of home monitoring with CNS Sleep I/T in patients with suspected obstructive sleep apnea. Am Rev Respir Dis 1993; 147:A808. |
| Ferguson KA, Keenan SP, Love LL, Al-Majed SA, Fleetham JA. Validation of home monitoring with CNS Poly G/Sleep I/T in patients with obstructive sleep apnea. Am J Respir Crit Care Med 1994;149:A51. |
| Ferguson KA, Ono T, Lowe AA, Keenan SP, Love LL, Fleetham JA. Oral appliances in the treatment of obstructive sleep apnea. Am J Respir Crit Care Med 1994;149:A494. |
| Keenan SP, MacDonald GE, Rutledge FS, Harris KA, Girotti MJ, Massel D, Sibbald WJ, Inman KJ. Factors associated with perioperative cardiac morbidity and mortality in high risk non-cardiac surgery: Picking patients for a transitional care unit. Crit Care Med 1995;23(1):A81 |
| Keenan SP, Doig GS, Martin CM, Inman KJ, Sibbald WJ. The appropriateness of patient admission to, and early discharge from, a Canadian ICU. Am J Respir Crit Care Med 1995;151(4):A493. |
| Keenan SP, MacDonald G, Massel D, Rutledge F, Girotti M, Harris K, Ryan H, Sibbald WJ, Inman KJ. Audit of a Vascular Surgery Transitional Care Unit. Am J Respir Crit Care Med 1995;151(4):A488. |
| Keenan SP, MacDonald GE, Rutledge FS, Harris KA, Girotti MJ, Massel D, Sibbald WJ, Inman KJ. A six month audit of vascular and general surgery patients admitted post-operatively to a Canadian Intensive Care Unit. Clinical and Investigative Medicine, 1995; 18(4):B21 |
| Marotta PJ, Gregor JC, Ponich TP, Howard JM, Sibbald WJ, Keenan SP, Baltzer M. Nutritional support in the intensive care unit: a cost-minimization analysis. OHCEN proceedings, November,1995 |
| Keenan SP, Gill RS, Rutledge FS, Sibbald WJ, Sharpe MD. Inhalational Prostaglandin E1 (PGE1) in patients with severe ARDS. Am J Respir Crit Care Med 1996;153(4):A441 |
| Keenan SP, Busche K, Eberhard JA, Chen LM, Esmail R, Sibbald WJ, Inman KJ. The withdrawal of life support in the ICU: a comparison of incidence and process between teaching and community hospitals. Am J Respir Crit Care Med 1996;153(4):A384. |
| Keenan SP, Kernerman P, Cook D, Martin CM, McCormack D, Sibbald WJ. The effects of noninvasive positive pressure ventilation on mortality in patients with acute respiratory failure: a meta-analysis. Clinical and Investigative Medicine, 1996; 19(4):S94 |
| Keenan SP, Gregor JC, Inman KJ, Dhawan R, Sibbald WJ. Is the addition of noninvasive positive pressure ventilation in severe acute exacerbations of chronic obstructive pulmonary disease cost-effective? Crit Care Med 1997; 25(1):A91. |
| Dhawan R, Inman KJ, Keenan SP, Sibbald WJ. Does pulse oximetry make economic sense in the intensive care unit? Crit Care Med 1997; 25(1):A97 |
| Chen LM, Martin CM, Sibbald WJ, Keenan SP. Patients readmitted to the intensive care unit (ICU) during the same hospitalization: a multi-centre cohort study. Crit Care Med 1997; 25(1):A83 |
| Keenan SP, Busche KD, Chen LD, McCarthy L, Inman KJ, Sibbald WJ. A retrospective review of a large cohort of patients undergoing withholding or withdrawal of life support. Am J Respir Crit Care Med 1997 |
| Keenan S, Kossuth J, Eberhard J, Hoffmaster B, Sibbald W. Attitudes regarding organ donation from non-heart-beating donors. Proceedings of World Congress of Intensive and Critical Care Medicine, Ottawa, June, 1997 |
| Keenan S, Kossuth, Doig G, Inman K, Sibbald W. Critical Care Research Network (CCR-Net): a partnership in community-based research and research transfer. Proceedings of World Congress of Intensive and Critical Care Medicine, Ottawa, June, 1997 |
| Montgomery J, Keenan S, Esmail R, Inman K, Sibbald W. The process or ventilatory care in a selection of Ontario hospitals. Proceedings of World Congress of Intensive and Critical Care Medicine, Ottawa, June, 1997 |
| Kojlak J, Keenan S, Plotkin D, Fish N, Esmail R. Are the bereavement needs of families and healthcare workers currently being met? Proceedings of World Congress of Intensive and Critical Care Medicine, Ottawa, June, 1997 |
| Butler R, Block G, Sharpe M, Keenan S, Inman K. Modes of weaning from mechanical ventilation: a critical appraisal of the randomized trials. Proceedings of World Congress of Intensive and Critical Care Medicine, Ottawa, June, 1997 |
| Keenan SP, Martin CM, Chen LM, Sibbald WJ for the Critical Care Research Network. COPD patients requiring ICU admission: hospital outcome in a group of Canadian teaching and nonteaching hopsitals. Crit Care Med 1998; 26:A112. |
| Ostermann M, Keenan SP, Martin CM, Sibbald WJ. Effect of intermittent hemodialysis on the tissue-arterial gradient of gastric tonometry in patients with multiple organ failure. Am J Respir Crit Care 1998; 157:A297 |
| Ostermann M, Keenan SP, Seiferling R, Sibbald WJ. Sedation in the intensive care unit: a systematic review of the literature. Am J Respir Crit Care 1998; 157:A301 |
| Keenan SP, Dhawan R, Sinacori MC, Sibbald WJ. Advertising in intensive care unit technology in peer-reviewed journals: how well do they represent their products? Am J Respir Crit Care 1998; 157:A301. |
| Keenan SP, Mawdsley C, Plotkin D, Kossuth J, Sibbald WJ, for the Critical Care Research Network. The withdrawal of life support – can we do better?: a survey of nurse and respiratory therapist satisfaction levels. Am J Respir Crit Care 1998; 157:A303. |
| Keenan SP, Mawdsley C, Plotkin D, Kossuth J, Sibbald WJ, for the Critical Care Research Network. Nurse and respiratory therapist satisfaction with withdrawal of life support differs among hospitals. Am J Respir Crit Care 1999; 159:A916 |
| Heyland DK, Cook DJ, Griffith L, Keenan SP, Brun-Buisson C & Canadian Critical Care Trials Group. The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. Am J Respir Crit Care 1999; 159:A263 |
| Keenan SP, Hogg R, Chan K, Craib K, Anis A, Spinelli J, Dodek P. Length of ICU and hospital stay for Stroke and Chronic Obstructive Pulmonary Disease (COPD) differs among large community hospitals. Am J Respir Crit Care 2000; 1:A |
| Keenan SP, Hogg RS, Chan K, Craib KJP, Anis A, Spinelli J, Dodek P. Intensive Care Unit (ICU) admission is only a weak predictor of long-term mortality. Am J Respir Crit Care 2000; :A. |
| Dubord J, Dodek P, Chan K, Keenan S, Marion S. Hospital mortality in adult critical care patients with heart failure: does size of hospital matter? Am J Respir Crit Care 2000; :A |
| Keenan SP, Powers C, Block G, McCormack DG. Noninvasive ventilation (NPPV) for post-extubation respiratory failure: a randomized, controlled trial. Am J Respir Crit Care 2000; :A |
| Keenan SP, Plotkin D, Mawdsley C, Priestap F for the Critical Care Research Network (CCR-Net). Factors associated with family satisfaction with the process of withdrawal of life support. Am J Respir Crit Care 2001; 163:A897 |
| Keenan SP, Powers C, McCormack DG. Noninvasive ventilation in milder COPD exacerbations: an RCT. Am J Respir Crit Care 2001; 163:A250 |
| Keenan SP, Chan K, Simon M, Levy A, Hogg R, Spinelli J, Craib K, Dodek P. Survivors of ICU admission have lower hospital readmission rates. Am J Respir Crit Care 2001; 163:A688 |
| Simon M, Chan K, Keenan SP, Levy A, Dodek P. Inter-hospital referral as a risk factor for hospital mortality of critically ill patients. Am J Respir Crit Care 2001; 163:A689 |
| Tan-Ngo C, Chan K, Simon M, Keenan S, Dodek P. Acute Respiratory Distress Syndrome (ARDS) in British Columbia: regional variation in incidence and outcomes. Am J Respir Crit Care 2001; 163:A956 |
| Teja A, Chan K, Keenan S, Simon M, Levy A, Dodek P. Seasonality of bacterial pneumonia in a tertiary care intensive care unit. Am J Respir Crit Care 2001; 163:A25 |
| Dodek P, Keenan S, Heyland D, Cook D, Brun-Buisson C, Hall R, Jacka M, Foster D, Hand L, Mehta N, Muscedere J. Development of a clinical practice guideline for prevention of ventilator-associated pneumonia. Am J Respir Crit Care 2002;165:A37 |
| Sinuff T, Keenan SP, Cook DJ, Hill NS. Nonivasive positive pressure ventilation for acute exacerbations of chronic obstructive pulmonary disease: a systematic review. Am J Respir Crit Care 2002; 165:A796 |
| Belway D, Henderson W, Keenan SP, Levy AR, Dodek PM. Systematic review of effect of pretransport personnel on outcome of critically ill patients transferred between hospitals. Am J Respir Crit Care 2003 |
| Wong H, Thompson WD, Norena M, Keenan SP, Dodek PM. Relative value of severity of illness and comorbidity scores as predictors of hospital mortality, hospital length of stay and ICU length of stay. Am J Respir Crit Care 2003 |
| Keenan SP, Dodek PM, Norena M, Wong H. Hospital deaths associated with ICU admission: regional differences and associated variables. Am J Respir Crit Care 2003 |
| Sinuff T, Keenan SP, Cook DJ, Hill NS. Nonivasive positive pressure ventilation in acute hypoxemic respiratory failure: a meta-analysis. Am J Respir Crit Care 2003 |
| Dodek PM, Keenan SP, Norena M, Wong H. Structure, process and outcomes of all intensive care units with the province of British Columbia, Canada. Am J Respir Crit Care 2003 |
| Dodek PM, Keenan SP, Norena M, Martine CM, Levy A, Wong H. Geographic variation in key processes of care among intensive care units in British Columbia, Canada. Am J Respir Crit Care 2004; 169:A36 |
| Belway D, Dodek PM, Keenan SP, Norena M, Wong H, Henderson WH, Levy AR. Variation in transport times and outcomes for critically ill patients who are transferred to referral centers. Am J Respir Crit Care 2004; 169:A39 |
| Keenan SP, Martin CM, Norena M, Wong H, Dodek PM. Variation in length of ICU stay among ICUs for patients admitted after cardiac arrest. Am J Respir Crit Care 2004; 169:A624 |
| Dodek PM, Norena M, Keenan SP, Wong H. Seasonal variation in ICU admissions for pneumonia is not fully explained by weather or influenza reports in the community. Am J Respir Crit Care 2005; A424 |
| Keenan SP, Sinuff T, Cook DJ, Hill NS. Noninvasive positive pressure airway support in cardiogenic pulmonary edema (CPE), continuous positive airway pressur (CPAP) versus noninvasive ventilation (NIV): a systematic review. Am J Respir Crit Care 2005; A810 |
| Sinuff R, Burns KEA, Eva K, Adhikari N, Keenan SP, Rocker G, Hill N, Patel R, Mehta S, Heels-Ansdell D, Heyland D, Kacmarek R, Cook DJ. Nonivasive ventilation (NIV) for acute respiratory failure (ARF) near or at the end-of-life. Am J Respir Crit Care 2005; A810 |
| Dodek P, Norena M, Wong H, Keenan SP, Martin CM. Role of organizational factors in hospital mortality for ICU Patients in Canada. Am J Respir Crit Care 2006; A380 |
| Khan NA,, Palepu A, Hameed SM, Norena M, Wong, H, Keenan SP, Ayas N, Chittock D, Dodek P. Impact of Racial/Ethnicity on Hospital Mortality for ICU Patients. Am J Respir Crit Care 2006; A298 |
| Muscedere J, Heyland D, Dodek P, Keenan S, Cook D. Evidence-based clinical practice guidelines for ventilator-associated pneumonia: diagnosis and treatment. Am J Respir Crit Care 2007:175:A105 |
| Dodek PM, Muscedere J, Heyland DK, Cook DJ, Keenan SP. Prevention of ventilator-associated pneumonia: updated evidence-based clinical practice guidelines. Am J Respir Crit Care 2007;175:A217 |
| Meade MO, Cook DJ, Arabi Y, Slutsky AS, Baxter A, Ronco JJ, Keenan S, Davies A, Hand L, Stewart TE. A multinational RCT of a Lung Open Ventilation Strategy in ALI/ARDS – preliminary results. Am J Respir Crit Care 2007;175:A507 |
| Sinuff T, Adhikari NKJ, Geerts S, Curtis JR, Cook DJ, Keenan SP, Hill NS. Noninvasive ventilation for patients with acute respiratory failure in the setting of a do-not-intubate decision: systematic review. Am J Respir Crit Care 2007;175:A787 |
| Martin CM, Priestap F, Heyland DK, Longo CJ, Fowler RA, Keenan SP, Fisher H. Treatment and mortality of severe sepsis: results of a canadian multicentre prospective observational study. Intensive Care Med 2008; 34 (supp 1):92. |
| Meade MO, Cook DJ, Mehta S, Arabi YM, Keenan S, Ronco JJ, Adhikari NK,Jacka M, Freitag A, Friedrich J, Granton JT, Patel R, Dorscheid D, Ferguson ND. A Multicentre Pilot Randomized Trial of High Frequency Oscillation in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med April 2009;179. |
| Keenan S, Sinuff T, Dodek P, Burns K, Muscedere J, Kutsogiannis J, Ayas N, Mehta S, Scales D, Adhikari N, Pagnotta R, Hand L, Lazosky L, Cook D, Sanders K, Dial S, Jaeschke R, Rocker G, Laupland K. Clinical practice guidelines (CPGs) for mask CPAP (CPAP) and Noninvasive ventilation (NIV) in acute care settings. Am J Respir Crit Care Med April 2009;179. |
| Burns KEA, Adhikari NJ, Keenan SP, Meade MO. Use of noninvasive ventilation to wean critically ill adults from invasive ventilation: a meta-analysis. Am J Respir Crit Care Med April 2009;179. |
| Sinuff T, Muscedere J, Cook D, Dodek P, Keenan S, Haupt M, Wood G, Tan R, Anderson W, Miletin M, Bouali R, Heyland D. Measuring appropriate guideline use in the ICU: guideline adherence or concordance? Am J Respir Crit Care Med April 2009;179. |
| Sinuff T, Muscedere J, Cook D, Dodek P, Keenan S, Haupt M, Wood G, Tan R, Anderson W, Miletin M, Bouali R, Heyland D. High prevalence of guidelines and patient safety initiatives in the ICU. Am J Respir Crit Care Med April 2009;179. |
| Sinuff T, Muscedere J, Cook D, Dodek P, Keenan S, Haupt M, Wood G, Tan R, Anderson W, Miletin M, Bouali R, Heyland D. Concordance with guidelines to prevent ventilator associated pneumonia (VAP). Am J Respir Crit Care Med April 2009;179. |
| Muscedere J, Sinuff T, Cook D, Dodek P, Keenan S, Wood G, Tan R, Anderson W, Haupt M, Bouali R, Miletin M, Jiang X, Heyland D. Variation in Tracheostomy practice. Am J Respir Crit Care Med April 2009;179. |
| Muscedere J, Sinuff T, Cook D, Dodek P, Keenan S, Wood G, Anderson W, Haupt M, Bouali R, Miletin M, Tan R, Jiang X, Heyland D. Outcomes and predictors of long-term ventilation in patients mechanically ventilated more than 48 hours. Am J Respir Crit Care Med April 2009;179
Mabasa VH, Khangura S, Wiens W, Reynolds S, Keenan S, Malyuk DL, Leung V, Full vs. Renal Dosing of Antibiotics in Septic Shock Patients With Acute Renal Failure: The FRASER Feasibility Trial(SCCM Abstract 876) Crit Care Med 2009;37(12):Supp A429 Society of Critical Care Medicine Annual Congress 2010 |
| Burns KEA, Lellouche F, Lessard M, Hand L, Zhou Q, Keenan SP, Meade M. Wean earlier and automatically with new technology: preliminary results ofe the WEAN study. Am J Respir Crit Care Med 2011:A6248 |
| Muscedere J, Sinuff T, Cook DJ, Dodek P, Keenan S, Wood G, Tan R, Anderson W, Haupt M, Bouali R, Miletin M, Jiang X, Heyland D. Active Observational Study of The Adoption and Transder of clinical practice guideliens through education, for ventilator associated pneumonia: The ABATE VAP Study. Am J Resp Crit Care Med 2011;183:A3736
Dodek PM, Hamric A, Ayas N, Dhingra V, Heppell L, Keenan S, Tholin H, Wong H, Kuhl D, Alden L, Macllure M, Appleby A, Stuart M, Stewart M, Henrich N, Norena M, Rodney P. Moral distress in ICU Professionals is associated with profession and years of experience. Am J Respir Crit Care Med 2012;185:A1607 Clarke F, Zytaruk N, Fowler R, Heels-Ansdell D, Crowther M, Freitag A, Karachi T, Pagliarello G, Cade J, Bellomo R, Keenan S, Reynolds S, Wood G, Paunovic B, Plaxton W, Hollinger G, Chittock D, Poirier G, Lopes R, Mandourah Y, Shaikh N, Al-Hazimi M, Al-Azem A, Ostermann M, Brandao N, Costa Filho R, da Silva A, Teixeira C, Rocha M, Guimaraes H, Cook DJ. Physicians declining patient enrolment into clinical trials: incidence and insights. Am J Respir Crit Care Med 2012; 185:A2543. Mehta S, Burry L, Cook DJ, Steinberg M, Fergusson D, Hebert P, Herridge MS, Granton J, Ferguson ND, Devlin JW, Tanios M, Fowler R, Dodek PM, Burns KEA, Jacka M, Olafson K, Reynolds S, Keenan S, Skrobik Y, Kutsogiannis J, Antoni K, Meade M. SLEAP: A multicenter randomized trial of daily awakening in critically ill patients being managed with a sedation protocol. Am J Respir Crit Care Med 2012;185:A3882 Boyce K, Dillon EC, Perrott J, Malyuk DL, Mabasa V, Attfield E, McCormack G, Keenan S. A Drug Use Evaluation. Comparing Dexmedetomidine Use at 3 Fraser Health Authority Sites Relative to the Manufacturer’s Recommended Directions for Use (DECODE study). Presentation and Poster at the Canadian Society of Hospital Pharmacists, B.C. Branch, Residency Research Day, May 2013 Dodek PM, Griesdale D, Norena M, Wong H, Ayas N, Chittock D, Ronco J, Foster D, Keenan S, Reynolds S, Gani S, McKeown S, McAdams M. Association Between Indices Of Glucose Control And Hospital Mortality: Variation Among Hospitals. Am J Respir Crit Care Med 2014; 189: A4525. Dodek PM, Griesdale DEG, Norena M, Wong H, Ayas N, Chittock D, Ronco JJ, Foster D, Keenan SP, Reynolds S, Dhingra V, Gani S. Hyperglycemic Index and Hyperglycemic Time Index Are Associated with Nosocomial Infections in Critically Ill Patients who Receive Insulin Infusions. Am J Respir Crit Care Med 2015;191:A6219. |
3. BOOKS
|
| Granting Agency | Subject | Funding Details | Year | Principal Investigator | Co-Investigator(s) | |||||||||
| CIHR | Canadian Critical Care Knowledge Translation Network | 2012-15 | J Muscedere | N Gibney, SKeenan,B Lawless, M. Legare,W. Patrick, B.Paunovic, S. Shaw, J.Trpkovski, C. Chant, DJ Cook, PM Dodek, DK Heyland, J Lacroix, CM Martin, SC Reynolds, DC Scales, T Sinuff, AF Turgeon
, |
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| CIHR (partners: CHEOS, SPH Foundation, PHC Research Institute, B.C. Patient Safety and Quality Council, BCNU, BC Chair in Patient Safety) |
The Relationship between Moral Distress in Health Care Workers and Patient Safety in Intensive Care Units | 2010-2012 | P Dodek | M Stuart, M Stewart, L Heppell, S Keenan, V Dhingra, D Kuhl, L Alden, L Hamric, N Henrich, P Rodney, N Ayas, M Maclure, H Wong, A Maudee, H Tholin | ||||||||||
| Respironics Inc. | Proposal for Development of Evidence-Based Clinical Practice Guidelines for the use of Noninvasive Positive Pressure Ventilation in the Acute Care Setting | 2007/07 – 2007/12 | Sean Keenan | Tasim Sinuff Peter Dodek Deborah Cook Karen Burns John Muscedere |
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| Canadian Institute for Health Research | Active Observational Study of the Adoption and Transfer of Clinical Practice Guidelines through Education, for Ventilator Associated Pneumonia | 2006/07 – 2009/06 | John Muscedere Tasim Sinuff |
Deborah Cook Daren Heyland Brenda Morgan Peter Dodek Redouane Bouali Zahra Punja Lori Hand Kevin Era Sean Keenan |
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| Canadian Institute for Health Research | Scoping and systematic review of noninvasive mechanical ventilation: laying the groundwork for the development of clinical practice guidelines | 2006/07 – 2006/12 | Peter Dodek | Sean Keenan Tasim Sinuff Deborah Cook Karen Burns John Muscedere |
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| Canadian Intensive Care Foundation | Clinical Practice Guidelines in the Intensive Care Unit: A Canadian Survey | 2004 | T Sinuff | D Cook
M Meade D Heyland P Dodek S Keenan G Rocker J Hutchison G Ellrodt |
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| Michael Smith Foundation for Health Research – Investigative Teams Program | ICU Patient Safety Team | 2005/07 – 2005/12 | Peter Dodek Najib Ayas |
Dean Chittock Sean Keenan Daren Heyland Mark Fitzgerald Sam Sheps Sandra Robinson Hubert Wong Rebecca Warburton |
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| Canadian Institutes of Health Research | Geographic variation in outcomes of critical care in BC: the role of ICU organizational factors | 2003/07 – 2003/12 | Peter Dodek | Sean Keenan, Hubert Wong, Adrian Levy | ||||||||||
| B.C. Medical Services Foundation | Determinants of outcomes for critically ill patients who are transported between hospitals | 2002/07 – 2002/12 | Peter Dodek | Sean Keenan, Dean Belway, William Henderson, A. Levy, H. Wong | ||||||||||
| Vancouver Coastal Health Authority Interdisciplinary Research Grant | Survival Using Glucose Algorithm Regulation | 2002 | J Ronco | K Burns
DJ Cook SP Keenan J Muscedere T Sinuff W Henderson P Dodek |
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| Health Services Resource Fund, London Health Sciences Centre | Current levels of satisfaction with the process of withdrawal of life support in the ICU among family members of patients dying in the ICU | 1998/07 – 1998/12 | Keenan SP | C Mawdsley, D Plotkin, A Kirby | ||||||||||
| Ontario Thoracic Society | Current knowledge of mechanical ventilation of respiratory therapists and physicians caring for ventilated patients | 1998/07 – 1998/12 | Keenan SP | WJ Sibbald, | ||||||||||
| Siemens Electric | The process of ventilatory care in a selection of teaching and community hospitals of Ontario | 1997/07 – 1997/12 | Keenan SP | WJ Sibbald, G Doig | ||||||||||
| Health Services Research Fund, London Health Sciences Centre | Current levels of satisfaction with the process of withdrawal of life support in the intensive care unit among ICU nurses and respiratory therapists | 1997/07 – 1997/12 | Keenan SP | C Mawdsley, D Plotkin, J Kossuth | ||||||||||
| Respironics Inc. | A randomized controlled study of the use of noninvasive positive pressure ventilation for patients developing respiratory failure within 48 hours of extubation | 1996/07 – 1996/12 | Keenan SP | G Block, D McCormack, R Dhwan, K Inman | ||||||||||
| Respironics Inc. | Noninvasive positive pressure ventilation plus standard care, vs standard care alone | 1996/07 – 1996/12 | Keenan SP | D McCormack, G Block, R Dhawan, K Inman | ||||||||||
| Victoria Hospital Research Development Fund | Assessment and development of criteria for intensive care unit admission from the emergency dept in teaching and non-teaching hospitals | 1995/07 – 1995/12 | Keenan SP | C Martin, L Chen | ||||||||||
| Ontario Thoracic Society | Peri-operative cardiac morbidity and mortality: the impact of noninvasive monitoring and practice guidelines | 1994/07 – 1994/12 | Keenan SP | W J Sibbald | ||||||||||
Areas of special interest and accomplishments
| 1 | Critical Care: Noninvasive ventilation
· Research in the form of 2 small RCTs and an observational study · Led or participated in a number of systematic reviews on effectiveness of noninvasive ventilation · Co-led Canadian clinical practice guidelines for use of noninvasive ventilation in the acute setting · Member of European Respiratory Society/American Thoracic Society clinical practice guidelines for the acute setting · Numerous presentation at national and international conferences · Local teaching for UBC Critical Care Residents · Co-led the 2018 Royal College of Physician & Surgeons ebook chapter on Noninvasive ventilation and CPAP in “Navigating Medical Emergencies: An interactive guide to patient management” |
| 2 | Quality Improvement:
· Fraser Health Authority (FHA) Physician Quality Improvement (PQI) Cohort 1 (completed 2016) · Faculty of FHA PQI since 2018 · Modular Lead for Fundamentals (Level 2) FHA PQI – led curriculum renewal for transition to virtual platform (summer 2020). · Teacher for Level 3 PQI … Tools and Data, Advanced Data |
Courses Taught at UBC
| Year | Description | Total Number of Scheduled Hours | Class Size | Hours Taught | |||
| Lectures | Tutorials | Labs | Other | ||||
| 2019 | UBC Critical Care Fellowship Academic Rounds “Ethical and Legal Considerations in Organ Donation for the Intensivist | 1 | 5 | 1 | 4/5 | ||
| 2015 | UBC Critical Care Fellowship Academic Rounds “Quality & you: QI saving lives in ICU” | 1 | 5 | 1 | 4/5 | ||
| 2015 | UBC Critical Care Fellowship Academic Rounds “Noninvasive Ventilatory Support in Critical Care” | 1 | 5 | 1 | 5/5 | ||
| 2014 | UBC Critical Care Fellowship Academic Rounds “Interprofessional Conflict” | 1 | 5 | 1 | 5/5 | ||
| 2012 | UBC Critical Care Fellowship Academic Rounds “Managing interprofessional conflict” | 1 | 5 | 1 | Rated by Residents as Essential to their training | ||
| 2007 | UBC Critical Care Fellowship Academic Rounds “Noninvasive Ventilation in Acute Respiratory Failure” | 1 | 5 | 1 | Rated by Residents as Essential to their training | ||
| 2006 | Clinical exam/history for Respiratory System, 1st year UBC Students | 6 | 8 | 2 | |||
| 2005 | Fundamentals in Critical Care, Medical Residents, | 4 | 12 | 1 | 1 | ||
Unscheduled Teaching
| Description | Duration | Year | Number of Students / Trainees | Student / Trainee level | Total Hours |
| Teaching in Critical Care Units | 6 weeks | 2020 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 30 |
| Teaching in Critical Care Units | 13 weeks | 2019 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 65 |
| Teaching in Critical Care Units | 13 weeks | 2018 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 65 |
| Teaching in Critical Care Units | 13 weeks | 2017 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 65 |
| Teaching in Critical Care Units | 13 weeks | 2016 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 65 |
| Teaching in Critical Care Units | 15 weeks | 2015 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 75 |
| Teaching in Critical Care Units | 15 weeks | 2014 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 75 |
| Teaching in Critical Care Units | 15 weeks | 2013 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 75 |
| Teaching in Critical Care Units | 15 weeks | 2012 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 75 |
| Teaching in Critical Care Units | 15 weeks | 2011 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 75 |
| Teaching in Critical Care Units | 15 weeks | 2010 | 4-6 per week | Med Year 4, PGY 1,2,3, 4, ICU Fellow | 75 |
| Teaching in Critical Care Units | 15 weeks | 2009 | 2-3 per week | Med Year 4, PGY 1,2,3, | 75 |
| Teaching in Critical Care Units | 15 weeks | 2008 | 2-3 per week | Med Year 4, PGY 1,2,3, | 75 |
| Teaching in Critical Care Units | 15 weeks | 2007 | 2-3 per week | Med Year 4, PGY 1,2,3, | 75 |
| Teaching in Critical Care Units | 12 weeks | 2006 | 2-3 per week | Med Year 4, PGY 1,2,3, | 60 |
| Teaching in Critical Care Units | 12 weeks | 2005 | 2-3 per week | Med Year 4, PGY 1,2,3, | 60 |
| Teaching in Critical Care Units | 12 weeks | 2004 | 2 per week | PGY 1 | 60 |
| Teaching in Critical Care Units | 10 weeks | 2003 | 2 per week | PGY 1 | 50 |
| Teaching in Critical Care Units | 10 weeks | 2002 | 2 per week | PGY 1 | 50 |
| Teaching in Critical Care Units | 10 weeks | 2001 | 2 per week | PGY 1 | 50 |
| Teaching in Critical Care Units | 10 weeks | 2000 | 2 per week | PGY 1 | 50 |
| Teaching in Critical Care Units | 6 weeks | 1999 | 2 per week | PGY 1 | 30 |
| Teaching Respiratory Medicine | 8 weeks | 2006 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |
| Teaching Respiratory Medicine | 8 weeks | 2005 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |
| Teaching Respiratory Medicine | 8 weeks | 2004 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |
| Teaching Respiratory Medicine | 8 weeks | 2003 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |
| Teaching Respiratory Medicine | 8 weeks | 2002 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |
| Teaching Respiratory Medicine | 8 weeks | 2001 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |
| Teaching Respiratory Medicine | 8 weeks | 2000 | 2 per week | PGY 1, PGY 3 (Anesth) | 40 |