Dr. David Sweet
Dr. Sweet received an MD with honours from the University of Alberta in 2002, subsequently, he completed residency in emergency medicine and a fellowship in critical care medicine through the University of British Columbia.
He is on staff in the ICU at Vancouver General Hospital. Dr Sweet has been the clinical lead for sepsis with the BC Patient Safety and Quality Council since 2011. His interests focus on sepsis research, sepsis quality improvement, and education. In 2015 Dr. Sweet received the Global Sepsis award for the recent advances in sepsis care in British Columbia.
Academic Advisor role for Critical Care fellow Emma Schon
Pacific North West/North Americas Sepsis Conference organizing committee
• Member of the organizing committee for the largest stand alone sepsis conference in the United States.
Clinical Associate Professor of Medicine 2016-present
University of British Columbia
Transesophageal Echocardiograpy Fellowship 2010
Completed 3 months of full time training in TEE
Passed National Board of Echocardiography Basic Transesophageal
Echocardiography Exam (above 95% percentile)
Clinical Assistant Professor of Medicine 2010-2016
University of British Columbia
Attending Critical Care Physician FRCP(C) 2011-present
Faculty of Medicine, Department of Medicine
Surrey Memorial Hospital
Attending Critical Care Physician FRCP(C) 2008-present
Faculty of Medicine, Department of Medicine
Vancouver General Hospital
Attending Emergency Physician FRCP(C) 2007-present
Vancouver General Hospital
VGH ICU Medical Student/Resident Director of Education 2008-present
University of British Columbia
Chief Resident of Critical Care Medicine FRCPC program 2008
Faculty of medicine, Department of Medicine
University of British Columbia, Vancouver, BC
Chief Resident of Emergency Medicine FRCPC program 2005
Faculty of Medicine, Department of Surgery
University of British Columbia, Vancouver, BC
General License to Practice Medicine 2004
College of Physician and Surgeons of British Columbia
Registration number 17332
Completion of General Internship year July 2002-June 2003
Royal Columbian Hospital, Vancouver, BC
University of Alberta, Edmonton, AB Sept. 1998 -June 2002
Faculty of Medicine and Dentistry
Doctor of Medicine with Honors in Research
Gold Medalist and Governor General’s Silver Medalist
University of Calgary, Calgary, AB Sept. 1994 – April 1998
Bachelor of Science (BSc)
First class honors in Cellular, Molecular and Microbial Biology
Honors in Research
Cumulative GPA: 3.97 on 4.0 scale
College of Physicians & Surgeons Province of British Columbia (BCMA)
Canadian Medical Association (CMA)
Canadian Association of Emergency Physicians (CAEP)
BC Society of Critical Care Medicine
QUALITY IMPROVEMENT/KNOWLEDGE TRANSLATION
Sepsis Clinical Lead- BC Patient Safety and Quality Council 2014-present
- Lead the provincial wide quality improvements initiatives by the BCPSQC. This includes education and QI at all levels of care from the front line to policy development. This includes leading the BC Sepsis Network which is a group of approximately 300 clinicians engaged in Sepsis Quality improvement across the province of BC.
British Columbia Antimicrobial Review Work Team (ARWT) Committee
- Special committee formed to evaluate the addition of Remdesivir to formulary within the province during the pandemic.
British Columbia COVID-19 Therapeutics Review and Advisory Working Group 2020-2021
- Special subcommittee formed to evaluate the COVID Treatments within the province during the pandemic with an operational lens.
British Columbia COVID-19 Clinical Reference Group/Committee (CRG) 2020-2021
- Represent the CTC at the larger CRG that oversees all clinical recommendations for COVID-19 in British Columbia.
British Columbia COVID-19 Therapeutics Committee (CTC)- Founder and Chair March 2020-November 2021
- Founded, organized formation and chaired (for 20 months) of the provincial committee of 50 specialists to evaluate literature and make clinical recommendations for COVID-19 treatment and report to the CDC for bimonthly publication.
Asif Raza Khowaja 1, Alexander J Willms, Christina Krause, Sarah Carriere, Ben Ridout, Colleen Kennedy, Eric Young, Craig Mitton, Niranjan Kissoon, David D Sweet. The Return on Investment of a Province-Wide Quality Improvement Initiative for Reducing In-Hospital Sepsis Rates and Mortality in British Columbia, Canada. Crit Care Med. 2021 Sep 29.
Cheng MP, Cau A, Lee TC, Brodie D, Slutsky A, Marshall J, Murthy S, Lee T, Singer J, Demir KK, Boyd J, Ohm H, Maslove D, Goffi A, Bogoch II, Sweet DD, Walley KR, Russell JA; Angiotensin Receptor Blocker Coronavirus Study (ARBs) CORONA I. Acute Cardiac Injury in Coronavirus Disease 2019 and Other Viral Infections – A Systematic Review and Meta-Analysis. Crit Care Med. 2021. September 2021 – Volume 49 – Issue 9 – p 1558-1566
Paquette K, Sweet DD, Stentrom R, Stabler SN, Lawandi A, Akhter M, Davidson AC, Gavric M, Jinah R, Saeed R, Demir K, Sangsari S, Huang K, Mahpour A, Shamatutu C, Caya C, Troquet JM, Clark G, Wong T, Yansouni CP, Cheng MP. Neither Blood Culture Positivity nor Time to Positivity is Associated with Mortality among Patients Presenting with Severe Manifestations of Sepsis: The FABLED Cohort Study. Open Forum Infect Dis. 2021. In press.
Afra K, Chen L, Sweet D. Tocilizumab for hospitalized patients with COVID-19. CMAJ. 2021 March 9th.
Chang K, Harbin M, Shuster C, Griesdale D, Foster D, Sweet D, Wood M, Dhingra V. Adding Vitamin C to hydrocortisone lacks benefit in septic shock: a historical cohort study. Can J Anaesth. 2020 Sept 1st.
Stukas S, Hoiland R,…..Sweet D…..Wellington C, Sekhon M. The Association of Inflammatory Cytokines in the Pulmonary Pathophysiology of Respiratory Failure in Criticallyl Ill Patients With Coronavirus 2019. Critical Care Explorations. 2020 September.
Butler-Laporte G, Yansouni C, et al, Sweet D, Cheng M. Real-world Time to Positivity of 2 Widely Used Commericail Blood Culture Systems in Patients With Severe Manifestations of Sepsis: An Analysis of the FABLED Study. Open Forum Infectious Diseases. 2020 August 23.
Kumar DS, O’Neill SB, Johnston JC, Grant JM, Sweet D. SARS-CoV-2 infestion in a 76 year old man with negative results for nasopharyngeal swab and possible nosocomial transmission. CMAJ. 2020 April 24.
Cheng MP, Stenstrom R, Paquette K, Stabler SN, Akhter M, Davidson AC, Gavric M, Lawandi A, Jinah R, Saeed Z, Demir K, Huang K, Mahpour A, Shamatutu C, Caya C, Troquet JM, Clark G, Yansouni CP, Sweet D. Blood Culture Results Before and After Antimicrobial Administration in Patients with Severe Manifestations of Sepsis: A Diagnostic Study. Ann Intern Med. 2019 Sep 17.
Stenstrom R, Choi JI, Grafstein E, Kawano T, Sweet D, Bischoff T, Leung V, Halim S. Use of C-reactive protein can safely decrease the number of emergency department patients with sepsis who require blood cultures. CJEM 2017. 19: 24.
Gorley C, Lindstrom R, McKeown S, Krause C, Pamplin C, Sweet D, Marsden J, Kennedy C. Exploring distributed leadership in the BC Sepsis Network. Healthcare Management Forum. 2016.
McKeown s, Krause C, Shergill M, Siu A, Sweet D. Gamification as a strategy to engage and motivate clinicians to improve care. Healthcare Management Forum. 2016.
McCallum J, Sweet D, Kanji H. Assessment of Paramedic Ultrasound Curricula: A Systematic Review. Air Medical Journal. 2015, Nov. 34:6.
Andrew J Wormsbecker, David D Sweet, Shawna L Mann, Sophie Y Wang, Morris R Pudek, Luke YC Chen.Conditions associated with extreme hyperferritinemia (> 3000 μg/L) in adults. Internal Medicine Journal. 2015.
Mah GT, Turgeon R, Loh G, Tejani AM, Sweet DD. Ketamine and propofol in combination for adult procedural sedation and analgesia in the emergency department (Protocol). Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD011456. DOI: 10.1002/14651858.CD011456
Abu-Laban RB, Migneault D, Grant MR, Dhingra V, Fung A, Cook RC, Sweet D. Extracorporeal Membrane Oxygenation After Protracted Ventricular Fibrillation Cardiac Arrest: Case Report and Discussion. CJEM. (In Press 2014).
Cheung D, Owen D, Brar H, Sweet D, Yoshida E, Dalal B, Chen L. Hemophagocytic Lymphohistiocytosis in Adults: Two Instructive Cases. UBCMJ. 2013 Feb;4(2): 17-22.
Sol Gregory, Mark Vu, David Sweet, Erik Vu, Gordon Finlayson, Ross Brown, Alec Ritchie, Donald Griesdale, Vinay Dhingra, Anthony Papp, “Provincial Clinical Practice Guidelines for the Management of Major Burn Trauma” BCMJ. 2012 Nov;54(9) 456-64.
Ho K, Marsden J, Jarvis-Selinger S, Novak Lauscher H, Kamal N, Stenstrom R, Sweet D, Goldman R, Innes G., “A Collaborative Quality Improvement Model and Electronic Community of Practice to Support Sepsis Management in Emergency Departments: Investigating Care Harmonization for Provincial Knowledge Translation”, Journal of Medical Internet Research: Research Protocols, 1(2), 2012, 12-22
Sweet D, Marsden J, Krause C, Ho K, Russell J. Sepsis: The Simple Stuff Saves Lives. BCMJ. 2012 May;54(4):176-182
Russel J, Sweet D, Boyd J Wally K. Septic Shock Management and Challenges in Developing New Drug Therapies. Open Access Emergency Medicine 2012.
Djogovic D, Green R, Keyes R, Sweet D. et al. Canadian Association of Emergency Physicians Sepsis Treatment Checklist: Optimizing Sepsis Care in Canadian Emergency Departments. Can J Emerg Med January 2012 Vol: 14 No: 1
Fukushima E., Gill G., Abu-Laban R, Sweet D. Prevalence of Advance Directives Among Elderly Patients Attending an Urban Emergency Department. Can J Emerg Med. 2012 Mar;14(2):90-6.
Richards M, Sreenivasan G, Dhingra V, Sweet D, Shen L. Hemophagocytic Syndroms in Adult Intensive Care Units. J Intensive Care Med 2011 26: 343
Sweet D, Jaswal D, Fu W, Bouchard M, Sivapalan P, Jen R, Chittock D. Emergency Department Driven Sepsis Protocol Improves Delivery of Therapy in Severely Septic Patients Admitted to the Intensive Care Unit. Can J Emerg Med 2010; 12(5):414-420.
Green T, Bisjima K, Sweet D. A Case of Profound Metabolic Acidosis from Pyroglutamic Acidemia: An Under Appreciated cause of High Anion Gap Metabolic Acidosis. Can J Emerg Med 2010; 12(5):449-452.
Hohl C, Kelly-Smith, Young T, Sweet D, Schulzer M. The Effect of bolus dose Etomidate on cortisol levels, mortality, and health services utilization: A Systematic Review. Ann Emerg Med 2010; 56:105-113.
HD Kiers, A Litchfield, S Reynolds, D Griesdale, RT Gibney, P Pickkers, D Chittock and DD Sweet. Early goal-directed therapy of septic patients coming from the ward does not protect the kidneys. J of Crit Care 2010;25(4): 563-569
Sweet D, Naismith A, Keenan S, Sinuff T and Dodek P. Missed Opportunities for Non-invasive Positive Pressure Ventilation. Journal of Critical Care 2008 Mar;23(1):111-7
Sweet D, Isac G, Morrison B, Fenwick J, Dhingra V. Purulent pericarditis in a patient with rheumatoid arthritis treated with etanercept and methotrexate. Can J Emerg Med 2007; 9(1):40-42.
Cheng MP, Stenstrom R, Paquette K, Stabler S, Murtaza A, Davidson AC, Gavric M, Lawandi A, Jinah R, Saeed Z, Demir K, Huang K, Caya C, Troquet JM, Clark G, Yansouni CP, Sweet D. The effect of antimicrobial administration on blood culture positivity in patients with severe manifestations of sepsis. Oral presentation at ID Week 2019. Awarded best abstract in diagnostics.
Stenstrom R, Choi S, Grafstein E, Kawano T, Sweet D, Bischoff T, Leung V, Halim S. Use of C-reactive protein can safely decrese the number of emergency department patients with sepsis who require blood cultures. CJEM 2017. 19:24
Shergill M, Sweet D, McKeown S, Krause C. Saving 150 Lives in 150 Days Accelerating the spread of evidence-based sepsis protocols. BCPSQC Quality Forum, Feb 2014
McKeown S, Sweet D, Krause C, Marsden J, Morwick R, Puri Ajay, Smith K. Improving Sepsis Care across a Province through a Distributed Clinical Leadership Model. BMJ International Forum, London England, April 2013
McKeown S, Sweet D, Krause C, Marsden J, Morwick R, Puri Ajay, Smith K. Improving Sepsis Care across a Province. BCPSCQ Quality Forum. Feb 2013
Gregory S, Vu MP, Sweet D, Papp A, Vu E, Dhingra V, Brown R, Simons R. Canadian Major Burns Clinical Practice Guidelines. American Burn Association, 2012
- Sweet; J. Marsden; C. Krause; N. Kamal; A. Needs; K. Procter; K. Ho4; M. Ertel; R. Stenstrom; B. WoodleyImplementation of Emergency Department Sepsis Guidelines: A 3 Year Journey. Presented at IHI, Orlando 2011.
Hohl C, Kelly-Smith, Young T, Sweet D, Schulzer M The Effect of a Bolus Dose of Etomidate on Hemodynamics: A Systematic Review. Presented CAEP 2011
Sweet D, Jaswal D, Fu W, Bouchard M, Sivapalan P, Jen R, Chittock D Emergency Department Driven Sepsis Protocol Improves Delivery of Therapy in Severely Septic Patients Admitted to the Intensive Care Unit. Critical Care 2009
Yerman T, Neitzel A, Sweet D. The Frequency of ‘Goals of Care’ Discussions at the time of Critical Care Service Consultation. Critical Care 2009
HD Kiers, A Litchfield, S Reynolds, D Griesdale, RT Gibney, P Pickkers, D Chittock and DD Sweet. Early goal-directed therapy of septic patients coming from the ward does not protect the kidneys, Critical Care 2009
Sweet. D, Naismith A, Keenan S, Sinuff T and Dodek P. Missed Opportunities for Non-invasive Positive Pressure Ventilation. Am J Respir Crit Care Med 2004;169: A522
Fukushima E., and Gill G., Abu-Laban R, Sweet D. Prevalence of Advance Directives Among Elderly Patients Attending an Urban Emergency Department. Can J Emerg Med 2009
HD Kiers, A Litchfield, S Reynolds, D Griesdale, RT Gibney, P Pickkers, D Chittock and DD Sweet. Early goal-directed therapy of septic patients coming from the ward does not protect the kidneys from 29th International Symposium on Intensive Care and Emergency Medicine Brussels, Belgium. 24–27 March 2009. Critical Care 2009, 13(Suppl 1):P259
Russell JA, Linder A, Sweet D, Boyd J, Walley KR. Advances in Sepsis (Chapter 18). In Lalwani AK and Pfister MHF (eds) Recent Advances in Otolaryngology-Head and Neck Surgery, 4th Edition, Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, 2015, pp. xxx-xxx.
Julian Marsden, Noreen Kamal, Helen Novak Lauscher, Sandra Jarvis-Selinger, Anna Needs, David D. Sweet, Celine Cressman, Kendall Ho, “Evidence 2 Excellence: An Emergency Medicine Quality Improvement Model Utilizing Technology Enabled Interprofessional Collaboration in British Columbia”,Technology Enabled Knowledge Translation for eHealth: Principles and Practice, Springer., 2012.
NON-PEER REVIEWED PUBLICATIONS
Sweet D, Chittock D. New developments in the management of the critically-ill: We need to stop the bleeding. Critical Care Scientific Update; 2005. Snell Medical Communication Inc.
Special Service Award 2021
- Awarded by Vancouver Medical Dental Allied Staff Association. Awarded for work that in unique and extends beyond the walls of the institution. British Columbia COVID-19 Therapeutic’s Committee (Chair) September 2021
Best Abstract Award in Diagnostics; Infectious Diseases Society of America 2019 (USD $2000)
Honour Roll for Clinical Teaching Excellence 2017
- Awarded by UBC department of medicine for outstanding contributions to the clinical educational experience of residents and/or medical students.Nominations based on trainee evaluations with only top 10% of all teachers qualifying.
The Global Sepsis Award 2015
- Awarded annually to an individual who has had major contributions to the fight against sepsis. 3 awards giving out globally per year.
The Moshier Memorial Gold Medal June, 2002
- To be awarded annually to a student with superior academic achievement who is deemed to be the most outstanding graduating student in the MD program.
The Governor General’s Silver Medal June, 2002
- To be awarded annually to the undergraduate students who achieve the highest academic standing overall upon graduation from his/her degree program.
The Dr F Lloyd Roberts Scholarship June, 2002
- Awarded to a graduation student in medicine on the basis of outstanding merit in all studies in the Faculty of Medicine and Dentistry.
The EW Kuder Memorial Scholarship in Surgery June,2002
- To be awarded annually to a student with the highest marks intheir surgical rotation.
A Telus Mobility Scholarship in Emergency Medicine June,2002
- Awarded for distinction in a clinical Emergency Medicine on the basis of superior academic achievement.
The Charles T. Fried Memorial Award June,2002
- Awarded annually for outstanding merit in the field of pediatrics.
Edmonton Emergency Physicians Association Book Award 2001
A Harold and Opal Hess Bursary in Medicine August, 2001
The Dr Allan Coates Rankin Award August, 2000
- Awarded annually to the most deserving and outstanding student in Medicine completing any year of study.
Louise McKinney Scholarship for Post-Secondary Education August 2000 • Awarded to students whose academic achievement places them within
the top 1.5-2% of the university student body.
The Rose Bogoch Prize in Ophthalmology August 2000
- Awarded annually to a second year student for outstanding merit in the field of Ophthalmology.
Charles E Frosst Medical Bursary and Medal August 1999
- To be awarded annually to a student completing first or second year of Medicine on the basis of academic standing.
Dean’s Honours List (not available in 1998-1999)
1999–2000, 2000-2001, 2001-2002
CELLULAR, MOLECULAR AND MICROBIAL BIOLOGY DEGREE:
University of Calgary Dean’s List 1998, 1997, 1996, 1995
Louise McKinney Scholarship for Post-Secondary Education 1998, 1997, 1996,1995
University of Calgary Undergraduate Merit Award 1998, 1997, 1996, 1995
- Co-application for successful CIHR grant for RCT ARBs CORONA II with PI Jim Russell. $5,000,000. 2020.
- Co-applicant/Collaborator for successful Canadian Network Team Grant lead by Dr Alison Fox-Robischaud. $5,000,000. 2020
- Co-applicant for successfully awarded VCHRI grant for COVID-19 Associated Venous and Arterial Thromboembolism (CAVEAT) study $35,000. May 2020.
- Successfully awarded summer studentship research project (SSRP) funding for looking at the effects of antibiotics on the positivity of blood cultures in patients with severe sepsis and septic shock. $3200. May 2015
- Successfully awarded summer studentship research project (SSRP) funding for looking at the effects of antibiotics on the positivity of blood cultures in patients with severe sepsis and septic shock. $3200. May 2014
- Co-applicant for successful VCH Teams grant. Validation of rapid inexpensive methods to measure free cortisol in critically ill septic patients. $29,995.40. May 2014
- Co-applicant for successful CIHR grant. The total 3 year grant funding is $283,425. For project “A collaborative Quality Improvement and Electronic Community of Practice to Support Sepsis Management in Emergency Department: Investigating Care Harmonization for Provincial Knowledge Translation” 2010
- Co-applicant for Creation of simulation modules to teach trainees communication and collaboration skills. $8,962.00. Teaching and Learning Enhancement Fund, University of British Columbia. 2010
INVITED LECTURES 2021
2021 Sepsis update and provincial sepsis initiatives. October 2021. Special invitation to update Vancouver Island Health Authorities sepsis initiative. Vancouver Island Health Authority.
Initial Management of the Sick Septic Patient in the ED. September 2021 SPH virtual Emergency Medicine Conference Update. Whistler Virtual Conference.
“Trial(s) by jury? The case of Remdesivir. How much evidence does one need: reasonable cause to believe or beyond a reasonable doubt?“ University of Washington 9th Pacific Northwest Sepsis Conference– April 2021. International On-Line, Canada, USA, Africa (multiple countries), Brazil, Bangladesh.